发明公开
EP0667778A1 TREATMENT OF MELANOMA WITH ANTISENSE OLIGONUCLEOTIDES TO C-MYB PROTO-ONCOGENE
失效
治疗反义寡C-MYB原癌基因恶性黑色素瘤。
- 专利标题： TREATMENT OF MELANOMA WITH ANTISENSE OLIGONUCLEOTIDES TO C-MYB PROTO-ONCOGENE
- 专利标题（中）： 治疗反义寡C-MYB原癌基因恶性黑色素瘤。
-
申请号： EP92924379.0申请日： 1992-11-12
-
公开(公告)号： EP0667778A1公开(公告)日： 1995-08-23
- 发明人: GEWIRTZ, Alan, M. , CALABRETTA, Bruno
- 申请人： Temple University of the Commonwealth System of Higher Education , University of Pennsylvania
- 申请人地址： Broad Street and Montgomery Avenue Philadelphia PA 19122 US
- 专利权人： Temple University of the Commonwealth System of Higher Education,University of Pennsylvania
- 当前专利权人： Temple University of the Commonwealth System of Higher Education,University of Pennsylvania
- 当前专利权人地址： Broad Street and Montgomery Avenue Philadelphia PA 19122 US
- 代理机构： W.P. THOMPSON & CO.
- 优先权： US19910792999 19911115
- 国际公布： WO1993009789 19930527
- 主分类号： A61K31
- IPC分类号： A61K31 ; A61K48 ; C07H21 ; C12N15 ; A61K38
摘要：
Melanoma is treated by administering oligonucleotides having a nucleotide sequence complementary to at least a portion of the mRNA transcript of the human c-myb gene. These 'antisense' oligonucleotides are hybridizable to the c-myb mRNA transcript.
信息查询
