发明公开
EP0685234A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER
失效
ARZNEISTOFFZUSAMMENSETZUNG,DIE EINNUKLEINSÄURECOPOLYMERENTHÄLT。
- 专利标题: DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER
- 专利标题(中): ARZNEISTOFFZUSAMMENSETZUNG,DIE EINNUKLEINSÄURECOPOLYMERENTHÄLT。
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申请号: EP94907061.9申请日: 1994-02-17
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公开(公告)号: EP0685234A1公开(公告)日: 1995-12-06
- 发明人: YANO, Junichi , OHGI, Tadaaki
- 申请人: NIPPON SHINYAKU COMPANY, LIMITED
- 申请人地址: 14, Kisshoin Nishinosho Monguchicho Minami-ku Kyoto-shi Kyoto 601 JP
- 专利权人: NIPPON SHINYAKU COMPANY, LIMITED
- 当前专利权人: NIPPON SHINYAKU COMPANY, LIMITED
- 当前专利权人地址: 14, Kisshoin Nishinosho Monguchicho Minami-ku Kyoto-shi Kyoto 601 JP
- 代理机构: Kügele, Bernhard
- 优先权: JP54939/93 19930219
- 国际公布: WO9418987 19940901
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; A61K47/24 ; A61K47/44
摘要:
The invention aims at effectively utilizing a single-stranded nucleic acid copolymer, in particular, poly(adenylic acid-uridylic acid) and providing a drug composition having an antitumor effect. An example of the drug composition of the invention is one containing a lipid device, such as Lipofecting®, 3-O-(4-dimethylaminobutanoyl)-1,2-O-dioleylglycerol, 3-O-(2-dimethylaminoethyl)carbamoyl-1,2-O-dioleylglycerol, 3-O-(2-diethylaminoethyl)-carbamoyl-1,2-O-dioleylglycerol or 2-O-(2-diethyl-aminoethyl)carbamoyl-1,3-O-dioleylglycerol, and poly(adenylic acid-uridylic acid).
公开/授权文献
- EP0685234B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER 公开/授权日:2000-05-10
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