发明公开
- 专利标题： AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME
- 专利标题（中）： 胺衍生物和含有它们的皮肤制剂
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申请号： EP94910037.4申请日： 1994-03-17
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公开(公告)号： EP0691327A1公开(公告)日： 1996-01-10
- 发明人: OHASHI, Yukihiro , YADA, Yukihiro , TAKEMA, Yoshinori , FUJIMORI, Taketoshi , KAWAMATA, Akira , OSU, Hiroyuki , HIGUCHI, Kazuhiko , IMOKAWA, Genji , KUSUOKU, Hiroshi , OGAWA, Ayumi , FUJIMURA, Tsutomu
- 申请人： Kao Corporation
- 申请人地址： 14-10, Nihonbashi Kayabacho 1-chome Chuo-Ku Tokyo 103 JP
- 专利权人： Kao Corporation
- 当前专利权人： Kao Corporation
- 当前专利权人地址： 14-10, Nihonbashi Kayabacho 1-chome Chuo-Ku Tokyo 103 JP
- 代理机构： Hansen, Bernd, Dr. Dipl.-Chem., et al
- 优先权： JP19930057248 19930317; JP19930057249 19930317; JP19930057251 19930317; JP19930058875 19930318; JP19930060599 19930319; JP19930060600 19930319; JP19930060601 19930319; JP19930060602 19930319; JP19930060603 19930319; JP19930060604 19930319; JP19940020184 19940217; JP19940039480 19940310; JP19940041324 19940311
- 国际公布： WO1994021595 19940929
- 主分类号： C07C217/28
- IPC分类号： C07C217/28 ; A61K7/48 ; A61K31/13 ; C07C229/12 ; C07C237/06 ; C07C323/25
摘要：
An amine derivative of following general formula (I) or (II) (wherein R 1 represents a heteroatom-containing C 1 -C 40 hydrocarbon group which may have a ring structure, etc.; R 2 to R 6 each represent a C 1 -C 10 hydrocarbon group, hydrogen, etc.; A 1 represents (i) or R 15 -Z-R 16 (CH 2 ) n -; B 1 represents hydrogen, a C 1 -C 10 hydrocarbon group, nitrogen, etc.; and C 1 represents hydrogen, a C 1 -C 10 hydrocarbon group, nitrogen, alcohol residue, phosphoric acid residue, etc.); a dermatologic preparation containing the same; and a process for producing the amine derivative. The amine derivative has excellent effects of smoothing wrinkles and improving keratodermia.
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