发明公开
- 专利标题： AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME
- 专利标题（中）： 阿明衍生物及皮肤病制剂含
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申请号： EP94910037申请日： 1994-03-17
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公开(公告)号： EP0691327A4公开(公告)日： 1996-05-01
- 发明人: OHASHI YUKIHIRO , YADA YUKIHIRO , TAKEMA YOSHINORI , FUJIMORI TAKETOSHI , KAWAMATA AKIRA , OSU HIROYUKI , HIGUCHI KAZUHIKO , IMOKAWA GENJI , KUSUOKU HIROSHI , OGAWA AYUMI , FUJIMURA TSUTOMU
- 申请人： KAO CORP
- 专利权人： KAO CORP
- 当前专利权人： KAO CORP
- 优先权： JP5724893 1993-03-17; JP5724993 1993-03-17; JP5725193 1993-03-17; JP5887593 1993-03-18; JP6059993 1993-03-19; JP6060093 1993-03-19; JP6060193 1993-03-19; JP6060293 1993-03-19; JP6060393 1993-03-19; JP6060493 1993-03-19; JP2018494 1994-02-17; JP3948094 1994-03-10; JP4132494 1994-03-11
- 主分类号： A61K8/41
- IPC分类号： A61K8/41 ; A61K8/46 ; A61K8/49 ; A61K8/68 ; A61K31/13 ; A61Q17/04 ; A61Q19/00 ; A61Q19/08 ; C07C215/08 ; C07C215/10 ; C07C215/12 ; C07C217/28 ; C07C219/06 ; C07C229/12 ; C07C229/24 ; C07C233/18 ; C07C235/10 ; C07C237/06 ; C07C323/25 ; C07D295/088 ; C07D311/58 ; C07D311/72 ; C07D317/22 ; C07F7/08 ; C07F9/09 ; C07H15/04 ; A61K7/48
摘要：
An amine derivative of following general formula (I) or (II) (wherein R1 represents a heteroatom-containing C¿1?-C40 hydrocarbon group which may have a ring structure, etc.; R?2 to R6¿ each represent a C¿1?-C10 hydrocarbon group, hydrogen, etc.; A?1¿ represents (i) or R?15-Z-R16(CH¿2)n-; B1 represents hydrogen, a C¿1?-C10 hydrocarbon group, nitrogen, etc.; and C?1¿ represents hydrogen, a C¿1?-C10 hydrocarbon group, nitrogen, alcohol residue, phosphoric acid residue, etc.); a dermatologic preparation containing the same; and a process for producing the amine derivative. The amine derivative has excellent effects of smoothing wrinkles and improving keratodermia.
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