发明授权
- 专利标题: VERFAHREN ZUR HERSTELLUNG UND ZÜCHTUNG HÄMATOPOETISCHER VORLÄUFERZELLEN
- 专利标题(英): Process for producing and breeding haematopoetic precursor cells
- 专利标题(中): 用于生产和育种造血祖细胞
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申请号: EP95925778.3申请日: 1995-06-28
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公开(公告)号: EP0716689B1公开(公告)日: 2002-10-02
- 发明人: BEUG, Hartmut , WESSELY, Oliver , STEINLEIN, Peter , DEINER, Eva , VON LINDERN, Maartje, Marie
- 申请人: Boehringer Ingelheim International GmbH
- 申请人地址: Binger Strasse 173 55218 Ingelheim am Rhein DE
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: Binger Strasse 173 55218 Ingelheim am Rhein DE
- 优先权: DE4422667 19940630
- 国际公布: WO96000777 19960111
- 主分类号: C12N5/00
- IPC分类号: C12N5/00 ; C12N5/08
摘要:
A process for the in vitro production of non-immortalised haematopoetic precursor cells of the erythroid line in which a population of erythroid precursor cells is exposed to a combination of growth factors containing a glucocorticoid and an oestrogen and at least one ligand of a tyrosine kinase receptor until the cells begin to renew themselves spontaneously.
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