发明公开
EP0722448A4 O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY
失效
O-芳基,O-烷基,O-烯基和O-炔基大环内酯类WITH免疫抑制活性
- 专利标题: O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY
- 专利标题(中): O-芳基,O-烷基,O-烯基和O-炔基大环内酯类WITH免疫抑制活性
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申请号: EP94931789申请日: 1994-09-30
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公开(公告)号: EP0722448A4公开(公告)日: 1998-04-29
- 发明人: GOULET MARK , ORGAN HELEN M , PARSONS WILLIAM H , SINCLAIR PETER J , WONG FREDERICK , WYVRATT MATTHEW J
- 申请人: MERCK & CO INC
- 专利权人: MERCK & CO INC
- 当前专利权人: MERCK & CO INC
- 优先权: US13207293 1993-10-04
- 主分类号: A61K31/41
- IPC分类号: A61K31/41 ; A61K31/40 ; A61K31/435 ; A61K31/445 ; A61P17/00 ; A61P29/00 ; A61P31/12 ; A61P37/06 ; C07D498/18 ; C07D491/16
摘要:
Substituted compounds of the FK-506 Type. These compounds are useful for the same or essentially the same purposes as FK-506 and are applied in the same or a similar manner. These compounds are immunosuppressants and useful for the treatment of autoimmune diseases, infectious diseases and/or the prevention of rejection of foreign organ transplants. Still other uses are described in the disclosure.
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