发明公开
EP0729362A1 TRANSDERMAL COMPOSITION OF N- N- 5- 4-(AMINOIMINOMETHYL)PHENYL]-1-OXOPENTYL]-L-$g(a)-ASPARTYL]-L-PHENYLALANINE OR ITS ESTERS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS
失效
N-（N-（5-（4-（氨基亚氨基甲基）苯基-1-氧代戊基）的透皮组合物-L-α-天冬氨酰基）-L-苯丙氨酸或酯衍生物及其盐PHARMAZEUTISCHVERWENDBAREN
- 专利标题： TRANSDERMAL COMPOSITION OF N- N- 5- 4-(AMINOIMINOMETHYL)PHENYL]-1-OXOPENTYL]-L-$g(a)-ASPARTYL]-L-PHENYLALANINE OR ITS ESTERS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS
- 专利标题（中）： N-（N-（5-（4-（氨基亚氨基甲基）苯基-1-氧代戊基）的透皮组合物-L-α-天冬氨酰基）-L-苯丙氨酸或酯衍生物及其盐PHARMAZEUTISCHVERWENDBAREN
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申请号： EP94931926.0申请日： 1994-10-24
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公开(公告)号： EP0729362A1公开(公告)日： 1996-09-04
- 发明人: FEIGEN, Larry, P. , GRIFFIN, Martin, John
- 申请人： G.D. SEARLE & CO.
- 申请人地址： Corporate Patent Department P.O. Box 5110 Chicago IL 60680-5110 US
- 专利权人： G.D. SEARLE & CO.
- 当前专利权人： G.D. SEARLE & CO.
- 当前专利权人地址： Corporate Patent Department P.O. Box 5110 Chicago IL 60680-5110 US
- 代理机构： Beil, Hans Christoph, Dr., et al
- 优先权： US19930155044 19931119
- 国际公布： WO1995013825 19950526
- 主分类号： A61K9
- IPC分类号： A61K9 ; A61K38 ; A61P7
摘要：
The present invention is for pharmaceutical compositions and a method of use for the transdermal delivery of N-[N-[5-[4-(aminoiminomethyl)phenyl]-1-oxopentyl]-L-α-aspartyl]-L-phenylalanine or its esters and their pharmaceutically acceptable salts which are useful as platelet aggregation inhibitors. In formula (I), R can be independently hydrogen or alkyl having 1 to 6 carbon atoms.
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