发明授权
EP0738152B1 USE OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES AS COLON CANCER CHEMOPREVENTATIVE AND CHEMOTHERAPEUTIC AGENTS
失效
用2-羟基-5- phenylazobenzoic衍生物用于预防CHEMO作为活性成分和结肠癌的化疗
- 专利标题： USE OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES AS COLON CANCER CHEMOPREVENTATIVE AND CHEMOTHERAPEUTIC AGENTS
- 专利标题（中）： 用2-羟基-5- phenylazobenzoic衍生物用于预防CHEMO作为活性成分和结肠癌的化疗
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申请号： EP95907293.5申请日： 1995-01-06
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公开(公告)号： EP0738152B1公开(公告)日： 2005-11-02
- 发明人: JOHNSON, Lorin K. , SLEISENGER, Marvin H.
- 申请人： SALIX PHARMACEUTICALS, INC.
- 申请人地址： 3600 W. Bayshore Road Palo Alto, CA 94303 US
- 专利权人： SALIX PHARMACEUTICALS, INC.
- 当前专利权人： SALIX PHARMACEUTICALS, INC.
- 当前专利权人地址： 3600 W. Bayshore Road Palo Alto, CA 94303 US
- 代理机构： Sexton, Jane Helen
- 优先权： US178578 19940107
- 国际公布： WO1995018622 19950713
- 主分类号： A61K31/655
- IPC分类号： A61K31/655 ; A61K31/615 ; A61P35/00
摘要：
The present invention provides a method of colon cancer chemoprevention or chemotherapy comprising administering to an individual suffering from colon cancer or at risk to develop colon cancer a pharmaceutical composition comprising an effective amount of a 2-hydroxy-5-phenylazobenzoic acid derivative or an ester of an active metabolite or an oxidation product of an active metabolite thereof, or a pharmacologically acceptable salt of the 2-hydroxy-5-phenylazobenzoic acid derivative or an ester or an active metabolite or an oxidation product of an active matabolite thereof.
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