发明公开
EP0754038A1 USE OF BENZYLIDENE-MALONONITRILE DERIVATES FOR THE TREATMENT OF LEUKEMIA
失效
使用亚苄基MALONONITRILDERIVATE用于治疗白血病
- 专利标题： USE OF BENZYLIDENE-MALONONITRILE DERIVATES FOR THE TREATMENT OF LEUKEMIA
- 专利标题（中）： 使用亚苄基MALONONITRILDERIVATE用于治疗白血病
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申请号： EP95917619.0申请日： 1995-04-20
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公开(公告)号： EP0754038A1公开(公告)日： 1997-01-22
- 发明人: LEVITZKI, Alexander , GAZIT, Aviv , ROIFMAN, Chaim
- 申请人： YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM , THE HOSPITAL FOR SICK CHILDREN RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP
- 申请人地址： 46 Jabotinsky Street Jerusalem 91042 IL
- 专利权人： YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM,THE HOSPITAL FOR SICK CHILDREN RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP
- 当前专利权人： YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM,THE HOSPITAL FOR SICK CHILDREN RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP
- 当前专利权人地址： 46 Jabotinsky Street Jerusalem 91042 IL
- 代理机构： Naismith, Robert Stewart, et al
- 优先权： US19940231717 19940422
- 国际公布： WO1995028922 19951102
- 主分类号： A61K31
- IPC分类号： A61K31
摘要：
The present invention relates to products and methods useful for treating leukemia, in particular acute lymphoblastomic leukemias. Compounds described herein are effective in inhibiting activities associated with ALL both in vitro and in vivo. Methods for modifying such compounds and screening other compounds are also provided in order to identify additional compounds with similar or better inhibition properties.
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