发明公开
EP0775119A1 PROCESSES AND INTERMEDIATES IN THE SYNTHESIS OF 5-(3- EXO-BICYCLO 2.2.1]HEPT-2-YLOXY]-4-METHOXYPHENYL)-3,4,5,6-TETRAHYDROPYRIMIDIN-2(1H)-ONE
失效
VERFAHREN UND ZWISCHENPRODUKTEFÜRDIE SYNTHESE VON 5-（3 EXO-BIZYKLO 2.2.1 HEPTYL-2-氧-4-甲氧基苯基）-3,4,5,6-四氢吡啶-2（1H） - 酮
- 专利标题： PROCESSES AND INTERMEDIATES IN THE SYNTHESIS OF 5-(3- EXO-BICYCLO 2.2.1]HEPT-2-YLOXY]-4-METHOXYPHENYL)-3,4,5,6-TETRAHYDROPYRIMIDIN-2(1H)-ONE
- 专利标题（中）： VERFAHREN UND ZWISCHENPRODUKTEFÜRDIE SYNTHESE VON 5-（3 EXO-BIZYKLO 2.2.1 HEPTYL-2-氧-4-甲氧基苯基）-3,4,5,6-四氢吡啶-2（1H） - 酮
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申请号： EP95915970.0申请日： 1995-05-04
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公开(公告)号： EP0775119A1公开(公告)日： 1997-05-28
- 发明人: LACOUR, Thomas, G. , MURTIASHAW, Charles, W.
- 申请人： PFIZER INC.
- 申请人地址： 235 East 42nd Street New York, N.Y. 10017 US
- 专利权人： PFIZER INC.
- 当前专利权人： PFIZER INC.
- 当前专利权人地址： 235 East 42nd Street New York, N.Y. 10017 US
- 代理机构： Moore, James William, et al
- 优先权： US19940286579 19940805
- 国际公布： WO1996004253 19960215
- 主分类号： C07C69
- IPC分类号： C07C69 ; C07C235 ; C07C255 ; C07C259 ; C07C271 ; C07D239
摘要：
This invention relates to novel processes for preparing the pharmaceutically active compound 5-(3-[(2S)-exo-bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl)-3,4,5,6-tetrahydropyrimidin-2(1H)-one and its corresponding 2R enantiomer and for preparing certain intermediates used in the synthesis of these compounds. It also relates to novel intermediates used in the synthesis of such pharmaceutically active compounds and to other novel compounds that are related to such intermediates.
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