发明公开
EP0801646A1 PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS
失效
药物PROPHYZAXE和中枢神经系统疾病的治疗
- 专利标题: PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS
- 专利标题(中): 药物PROPHYZAXE和中枢神经系统疾病的治疗
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申请号: EP95944395.0申请日: 1995-12-27
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公开(公告)号: EP0801646A1公开(公告)日: 1997-10-22
- 发明人: CROOKS, Peter, Anthony , CALDWELL, William, Scott , DULL, Gary, Maurice , BHATTI, Baldwinder, Singh
- 申请人: R.J. REYNOLDS TOBACCO COMPANY , The University of Kentucky Research Foundation
- 申请人地址: Bowman Gray Technical Center, P.O.Box 1487, 950 Reynolds Boulevard Winston-Salem North Carolina 27102 US
- 专利权人: R.J. REYNOLDS TOBACCO COMPANY,The University of Kentucky Research Foundation
- 当前专利权人: R.J. REYNOLDS TOBACCO COMPANY,The University of Kentucky Research Foundation
- 当前专利权人地址: Bowman Gray Technical Center, P.O.Box 1487, 950 Reynolds Boulevard Winston-Salem North Carolina 27102 US
- 代理机构: Shanks, Andrew, et al
- 优先权: US19950364976 19950106
- 国际公布: WO1996020929 19960711
- 主分类号: A61K31
- IPC分类号: A61K31 ; A61P25 ; C07D213 ; C07D239
摘要:
Patients susceptible to or suffering from central nervous system disorders are treated by administering an effective amount of an aryl substituted olefinic amine compound or an aryl substituted acetylenic compound. Exemplary compounds are (E)-N-methyl-4-[3-(6-methylpyrindin)yl]-3-butene-1-amine and N-methyl-4-(3-pyridinyl)-3-butyne-1-amine.
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