发明授权
EP0814086B1 ANTIBIOTICS TKR1912-I AND TKR1912-II AND PROCESS FOR PRODUCING THE SAME
失效
抗生素TKR1912 I和II TKR1912及其制造方法
- 专利标题: ANTIBIOTICS TKR1912-I AND TKR1912-II AND PROCESS FOR PRODUCING THE SAME
- 专利标题(中): 抗生素TKR1912 I和II TKR1912及其制造方法
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申请号: EP96905029.3申请日: 1996-03-08
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公开(公告)号: EP0814086B1公开(公告)日: 2002-07-24
- 发明人: TAKESAKO, Kazutoh , YOSHIKAWA, Yoshie , KOYAMA, Eiko , MASUDA, Tomoko , KATO, Ikunoshin
- 申请人: TAKARA SHUZO CO. LTD.
- 申请人地址: 609 Takenaka-cho Fushimi-ku Kyoto-shi, Kyoto 612 JP
- 专利权人: TAKARA SHUZO CO. LTD.
- 当前专利权人: TAKARA SHUZO CO. LTD.
- 当前专利权人地址: 609 Takenaka-cho Fushimi-ku Kyoto-shi, Kyoto 612 JP
- 代理机构: Hubert, Philippe
- 优先权: JP7975695 19950310
- 国际公布: WO9628456 19960919
- 主分类号: C07G11/00
- IPC分类号: C07G11/00 ; C12P1/04 ; A61K35/74 ; C12N1/20
摘要:
Novel antibiotics useful as a remedy for fungal infections and a process for producing antibiotic TKR1912-I or pharmacologically acceptable salts thereof, which substances have such physicochemical properties that (1) the mass spectrum thereof according to FAB-MS has a peak of m/z of 559 ÄM+HÜ ; (2) the molecule bears 26 carbon atoms and no nitrogen atom; (3) the ultraviolet absorption spectrum thereof in methanol shows a terminal absorptions; (4) the main absorption wavenumbers of the infrared absorption spectrum according to the KBr method are 3430, 2920, 2850, 1740, and 1190 cm ; and (5) they are soluble in methanol, chloroform, and water, but are sparingly soluble in hexane.
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