发明公开
- 专利标题: MESENCHYMAL STEM CELLS FOR CARTILAGE REPAIR
- 专利标题(中): 间充质干FOR修复软骨的
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申请号: EP96908794.0申请日: 1996-03-13
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公开(公告)号: EP0815203A1公开(公告)日: 1998-01-07
- 发明人: GRANDE, Daniel, A. , LUCAS, Paul, A.
- 申请人: Morphogen Pharmaceuticals, Inc. , North Shore University Hospital
- 申请人地址: 245 East 54th Street New York, NY 10022 US
- 专利权人: Morphogen Pharmaceuticals, Inc.,North Shore University Hospital
- 当前专利权人: Morphogen Pharmaceuticals, Inc.,North Shore University Hospital
- 当前专利权人地址: 245 East 54th Street New York, NY 10022 US
- 代理机构: Mercer, Christopher Paul
- 优先权: US19950403640 19950314
- 国际公布: WO1996028539 19960919
- 主分类号: A61F2
- IPC分类号: A61F2 ; A61K35 ; A61L27 ; C12N5
摘要:
It has been discovered that mesenchymal stem cells (MSCs) in a polymeric carrier implanted into a cartilage and/or bone defect will differentiate to form cartilage and/or bone, as appropriate. Suitable polymeric carriers include porous meshes or sponges formed of synthetic or natural polymers, as well as polymer solutions. A presently preferred material is a polyglycolic acid mesh.
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