发明公开
EP0823908A1 PYRIDO 2,3-d]PYRIMIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION
失效
吡啶并[2,3-D]蛋白介导的细胞传播的嘧啶类酪氨酸激酶作为抑制剂
- 专利标题： PYRIDO 2,3-d]PYRIMIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION
- 专利标题（中）： 吡啶并[2,3-D]蛋白介导的细胞传播的嘧啶类酪氨酸激酶作为抑制剂
-
申请号： EP96913175.0申请日： 1996-04-26
-
公开(公告)号： EP0823908A1公开(公告)日： 1998-02-18
- 发明人: BLANKLEY, Clifton, John , BOSCHELLI, Diane, Harris , DOHERTY, Annette, Marian , HAMBY, James, Marino , KLUTCHKO, Sylvester , PANEK, Robert, Lee
- 申请人： WARNER-LAMBERT COMPANY
- 申请人地址： 201 Tabor Road Morris Plains New Jersey 07950 US
- 专利权人： WARNER-LAMBERT COMPANY
- 当前专利权人： WARNER-LAMBERT COMPANY
- 当前专利权人地址： 201 Tabor Road Morris Plains New Jersey 07950 US
- 代理机构： Mansmann, Ivo, et al
- 优先权： US19950433294 19950503; US19960611279 19960403
- 国际公布： WO1996034867 19961107
- 主分类号： A61K31
- IPC分类号： A61K31 ; A61P9 ; A61P35 ; A61P43 ; C07D471
摘要：
6-Aryl pyrido[2,3-d]pyrimidine 7-imines, 7-ones, and 7-thiones o f formula (I) are inhibitors of protein tyrosine kinases, and are thus useful in treating cellular proliferation mediated thereby. The compounds are especially useful in treating cancer, atherosclerosis, restenosis, and psoriasis.
信息查询
