An interactive response system (20) includes a central control host system (22) and one or more wireless remote systems (23) geographically separated from the host system and interconnected with the host system through a communication network. Each remote system includes a base unit (26) and a plurality of response units coupled with the base units through a wireless communication link. Each of the response units includes a microphone (46), a user input device and a control. Audio signals entered through the microphone are communicated over the wireless communication channel to the base unit and over the communication network to the host system. Any inputs entered on the input device are communicated over the wireless communication channel to the base unit. The host system includes an instructor selection device and a display. At least one call list is displayed on the display. The instructor selects characteristics of individuals for inclusion on the call list. Individuals requesting to have an audio link with the instructor are placed on the call list if a characteristic of theirs from a database roster matches the characteristic set up by the instructor for that call list.