发明公开
- 专利标题： COMBINATORIAL 1,4-BENZODIAZEPIN-2,5-DIONE LIBRARY
- 专利标题（中）： 1,4-苯并二氮杂-2,5-二酮组合库
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申请号： EP96923532申请日： 1996-06-28
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公开(公告)号： EP0850238A4公开(公告)日： 1998-10-07
- 发明人: OHLMEYER MICHAEL H J
- 申请人： PHARMACOPEIA INC
- 专利权人： PHARMACOPEIA INC
- 当前专利权人： PHARMACOPEIA INC
- 优先权： US65795 1995-06-29
- 主分类号： C07D243/14
- IPC分类号： C07D243/14 ; C07D243/24 ; C07D487/04
摘要：
A method has now been found of synthesizing a combinatorial library of 1,4-benzodiazepin-2,5-diones on solid supports via an aza-Wittig ring closure, said compounds optionally encoded with tags, and to the use of this library in assays to discover biologically active compounds, and, optionally, to cleave 1,4-benzodiazepin-2,5-diones therefrom.
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