发明授权
- 专利标题: NOVEL EXPRESSION VECTORS AND METHODS OF USE
- 专利标题(中): 新型表达载体和使用方法
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申请号: EP96936537.8申请日: 1996-10-16
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公开(公告)号: EP0857217B1公开(公告)日: 2005-04-13
- 发明人: MARASCO, Wayne A. , RICHARDSON, Jennifer , PAROLIN, Maria Cristina , SODROSKI, Joseph G.
- 申请人: DANA-FARBER CANCER INSTITUTE
- 申请人地址: 44 Binney Street Boston, MA 02115 US
- 专利权人: DANA-FARBER CANCER INSTITUTE
- 当前专利权人: DANA-FARBER CANCER INSTITUTE
- 当前专利权人地址: 44 Binney Street Boston, MA 02115 US
- 代理机构: Brown, David Leslie
- 优先权: US5359P 19951016
- 国际公布: WO1997014809 19970424
- 主分类号: C12N15/86
- IPC分类号: C12N15/86
摘要:
The present invention is related to vectors and methods for increasing the expression of a desired gene product. Preferably this invention is used with genes expressing proteins that are not well tolerated by mammalian cells or where high levels of expression are necessary. In certain preferred embodiments it can be used as part of a multi-tiered expression system and with methods of intracellularly targeting a molecule.
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