发明公开
EP0915987A2 POLY-($g(a)-L-ASPARTIC ACID), POLY-($g(a)-L-GLUTAMIC ACID) AND COPOLYMERS OF L-ASP AND L-GLU, METHOD FOR THEIR PRODUCTION AND THEIR USE
失效
聚（α-L-天冬氨酸），聚（α-L-谷氨酸）和共聚物L-Asp和L-GLU，其生产和使用方法
- 专利标题： POLY-($g(a)-L-ASPARTIC ACID), POLY-($g(a)-L-GLUTAMIC ACID) AND COPOLYMERS OF L-ASP AND L-GLU, METHOD FOR THEIR PRODUCTION AND THEIR USE
- 专利标题（中）： 聚（α-L-天冬氨酸），聚（α-L-谷氨酸）和共聚物L-Asp和L-GLU，其生产和使用方法
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申请号： EP98922651.0申请日： 1998-04-06
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公开(公告)号： EP0915987A2公开(公告)日： 1999-05-19
- 发明人: TIRRELL, David, A. , DEL GROSSO, Michael , SIEGMEIER, Rainer , BOMMARIUS, Andreas
- 申请人： DONLAR CORPORATION , University of Massachusetts
- 申请人地址： 6502 South Archer Avenue Bedford Park, IL 60501 US
- 专利权人： DONLAR CORPORATION,University of Massachusetts
- 当前专利权人： DONLAR CORPORATION,University of Massachusetts
- 当前专利权人地址： 6502 South Archer Avenue Bedford Park, IL 60501 US
- 代理机构： Vossius, Volker, Dr., et al
- 优先权： US19970044727P 19970421
- 国际公布： WO1998048032 19981029
- 主分类号： C07K14
- IPC分类号： C07K14 ; C12P21
摘要：
The invention provides Poly-(α-L-aspartic acid) (= poly-L-α-Asp), Poly-(α-L-glutamic acid) and new copolymers of L-Asp and L-Glu with essentially α-linkages as well as salts of said polymers and copolymers. A method for producing said polyamino acids comprises employing an oligonucleotide construct encoding the sequence of the desired polymer, cloning the oligonucleotide into a plasmid, transformation of host cells with the plasmid and expression of the genetic information. Because of their good biological degradability the new poly-L-α-amino acids can be used as co-builders, sequestering agents and corrosion inhibitors.
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