发明授权
- 专利标题： FRAGMENTS D'ACIDES NUCLEIQUES SPECIFIQUES DE MYCOBACTERIES MEMBRES DU COMPLEXE M. TUBERCULOSIS) ET LEURS APPLICATIONS POUR LA DETECTION ET LE DIAGNOSTIC DIFFERENTIEL DES MEMBRES DU COMPLEXE M. TUBERCULOSIS
- 专利标题（英）： M. tuberculosis complex members mycobacteria specific nucleic acid fragments and their applications for the detection and differential diagnosis of m. tuberculosis complex members
- 专利标题（中）： 核酸片段特定于结核分枝杆菌复合的成员被用于检测及其应用鉴别诊断结核分枝杆菌复合成员的
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申请号： EP97937621.7申请日： 1997-08-12
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公开(公告)号： EP0918854B1公开(公告)日： 2004-10-27
- 发明人: MAGDALENA, Juana , SUPPLY, Philip , LOCHT, Camille
- 申请人： Institut Pasteur de Lille , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
- 申请人地址： 1, rue du Professeur Calmette 59019 Lille Cedex FR
- 专利权人： Institut Pasteur de Lille,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
- 当前专利权人： Institut Pasteur de Lille,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
- 当前专利权人地址： 1, rue du Professeur Calmette 59019 Lille Cedex FR
- 代理机构： Bernasconi, Jean Raymond
- 优先权： FR9610277 19960819
- 国际公布： WO1998007847 19980226
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; C12Q1/68 ; C07K14/35
摘要：
The invention concerns a M. tuberculosis complex mycobacteria specific fragment of nucleic acids, comprising a nucleotide chain selected among the SEQ ID NO. 1 sequence, the SEQ ID N 2 sequence, their complementary sequences or the nucleic acid sequences capable of being hybridised with one of the preceding sequences in conditions of high stringency. The invention also concerns uses of said sequences for the detection and differential diagnosis of mycobacteria members of the M. tuberculosis complex, in particular the BCG differential diagnosis of other members of the complex.
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