发明公开
EP0939815A1 IDENTIFICATION OF Bap-1, A PROTEIN THAT BINDS TO INTEGRIN AND IS INVOLVED IN INTEGRIN-MEDIATED SIGNAL TRANSDUCTION
失效
IDENTIFYING BAP-1，即整关系和整合素介导SIGNALUEBERTRAGUNG涉及到蛋白质
- 专利标题： IDENTIFICATION OF Bap-1, A PROTEIN THAT BINDS TO INTEGRIN AND IS INVOLVED IN INTEGRIN-MEDIATED SIGNAL TRANSDUCTION
- 专利标题（中）： IDENTIFYING BAP-1，即整关系和整合素介导SIGNALUEBERTRAGUNG涉及到蛋白质
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申请号： EP97949458.0申请日： 1997-11-18
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公开(公告)号： EP0939815A1公开(公告)日： 1999-09-08
- 发明人: LI, Shengfeng , PHILLIPS, David, R.
- 申请人： COR THERAPEUTICS, INC.
- 申请人地址： 256 East Grand Avenue, Suite 80 South San Francisco, CA 94080 US
- 专利权人： COR THERAPEUTICS, INC.
- 当前专利权人： COR THERAPEUTICS, INC.
- 当前专利权人地址： 256 East Grand Avenue, Suite 80 South San Francisco, CA 94080 US
- 代理机构： Mouget-Goniot, Claire, et al
- 优先权： US19960753038 19961118; US19970972719 19971118
- 国际公布： WO1998022583 19980528
- 主分类号： G01N33
- IPC分类号： G01N33 ; A61K45 ; A61P7 ; A61P29 ; A61P35 ; C07K14 ; C07K16 ; C07K17 ; C12N1 ; C12N5 ; C12N15 ; C12P21 ; C12Q1 ; A61K38
摘要：
The present invention provides the amino acid and nucleotide sequence of a protein that binds to β3 integrins, αIIb and Src kinase and is involved in integrin mediated signaling. Based on this disclosure, the present invention provides methods for identifying agents that block integrin mediated signaling, methods of using agents that block integrin mediated signaling to modulate biological and pathological processes, and agents that block integrin mediated signaling.
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