发明公开
- 专利标题: PYRAZOLE DERIVATIVES
- 专利标题(中): 吡唑衍生物
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申请号: EP97947901申请日: 1997-12-12
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公开(公告)号: EP0945438A4公开(公告)日: 2000-02-23
- 发明人: FUKAMI TAKEHIRO , FUKURODA TAKAHIRO , KANATANI AKIO , IHARA MASAKI
- 申请人: BANYU PHARMA CO LTD
- 专利权人: BANYU PHARMA CO LTD
- 当前专利权人: BANYU PHARMA CO LTD
- 优先权: JP35222596 1996-12-12
- 主分类号: C07D231/40
- IPC分类号: C07D231/40 ; C07D401/04 ; C07D401/12 ; C07D403/04 ; C07D403/12 ; C07D405/04 ; C07D405/12 ; C07D409/12 ; C07D487/04 ; A61K31/415 ; A61K31/44 ; A61K31/47
摘要:
Compounds represented by general formula (I), (wherein ring A and ring B are in a state of ortho fusion, the ring A representing an aromatic carbocyclic or heterocyclic ring, and the ring B representing a four- to seven-membered aliphatic carbocyclic or nitrogen-containing heterocyclic ring wherein the nitrogen atom can be present in only the site of fusion with the ring A; Ar represents an aromatic carbocyclic or heterocyclic group optionally substituted with a group selected among halogen atoms and lower alkyl, lower alkenyl, halogenated lower alkyl, lower alkoxy, lower alkylthio, lower alkylamino, di(lower alkyl)amino, and aromatic carbocyclic groups; and R represents a substituent selected among halogen atoms, nitro, lower alkyl, lower alkoxy, aromatic carbocyclic groups, and a carbonyl group having an aromatic carbocyclic group, or a hydrogen atom, provided that when the group represented by formula (a), is the group represented by formula (b), Ar represents neither phenyl nor 4-chlorophenyl) or salts thereof; a process for preparing the same; and a therapeutic agent for bulimia, obesity, or diabetes, comprising the compound or salt thereof as the active ingredient.
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