发明授权
- 专利标题： 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS
- 专利标题（中）： 3 PYRIDYLENANTIOMERE及其作为镇痛
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申请号： EP97952392.5申请日： 1997-12-10
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公开(公告)号： EP0950057B1公开(公告)日： 2002-11-13
- 发明人: HOLLADAY, Mark, W. , ARNERIC, Stephen, P. , BAI, Hao , DART, Michael, J. , LIN, Nan-Horng , LYNCH, John, K. , OR, Yat, Sun , RYTHER, Keith, B. , SULLIVAN, James, P. , WASICAK, James, T. , EHRLICH, Paul, P.
- 申请人： Abbott Laboratories
- 申请人地址： Chad 0377/AP6D-2, 100 Abbott Park Road Abbott Park, Illinois 60064-3500 US
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： Chad 0377/AP6D-2, 100 Abbott Park Road Abbott Park, Illinois 60064-3500 US
- 代理机构： Modiano, Guido, Dr.-Ing.
- 优先权： US763278 19961210; US32321P 19961210
- 国际公布： WO98025920 19980618
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; A61K31/44 ; C07D205/04
摘要：
The present invention relates to a method of controlling pain in mammals, including humans, comprising administering to a mammal or patient in need of treatment thereof selected compounds of formula (I) or a pharmaceutically acceptable salt thereof. The invention further relates to selected (R) and (S) compounds of formula (I) which are useful as analgesics as well as neuronal cell death preventors and anti-inflammatories.
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