发明公开
EP0960120A1 MAMMALIAN SEX COMB ON MIDLEG (MAMMALIAN Scm) ACTS AS AN ONCOGENE
失效
哺乳动物多肽（哺乳动物-SCM）甲癌基因的影响
- 专利标题： MAMMALIAN SEX COMB ON MIDLEG (MAMMALIAN Scm) ACTS AS AN ONCOGENE
- 专利标题（中）： 哺乳动物多肽（哺乳动物-SCM）甲癌基因的影响
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申请号： EP97924583.0申请日： 1997-05-06
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公开(公告)号： EP0960120A1公开(公告)日： 1999-12-01
- 发明人: RANDAZZO, Filippo
- 申请人： CHIRON CORPORATION
- 申请人地址： 4560 Horton Street Emeryville, California 94608-2916 US
- 专利权人： CHIRON CORPORATION
- 当前专利权人： CHIRON CORPORATION
- 当前专利权人地址： 4560 Horton Street Emeryville, California 94608-2916 US
- 代理机构： Goldin, Douglas Michael
- 优先权： US19960016876P 19960506; US19960017294P 19960513; US19960020450P 19960618; US19960032994P 19961216; US19970035090P 19970114
- 国际公布： WO1997042218 19971113
- 主分类号： C12N15
- IPC分类号： C12N15 ; A61K31 ; A61K38 ; A61K48 ; A61P35 ; A61P43 ; C07K14 ; C07K16 ; C12N5 ; C12P21 ; C12Q1
摘要：
Mammalian Scm gene and amino acid sequences encoded by the mammalian Scm gene, are described. The mammalian Scm gene and gene products are useful for diagnostic and therapeutic applications in proliferative and developmental disorders. Modulators of mammalian Scm can be identified using the disclosed genes. The modulators can be used in the context of cancer therapy or a treatment of a developmental disorder. Scm is also useful for inducing de-differentiation in a population of progenitor cells.
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