发明授权
- 专利标题: SUBSTITUTED 2,4-DIAMINOPYRIMIDINES
- 专利标题(中): 取代的2,4-二氨基
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申请号: EP98913585.0申请日: 1998-02-24
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公开(公告)号: EP0966464B1公开(公告)日: 2003-05-28
- 发明人: GUERRY, Philippe , HUBSCHWERLEN, Christian , JOLIDON, Synèse , SPECKLIN, Jean-Luc , WYSS, Pierre-Charles
- 申请人: Basilea Pharmaceutica AG
- 申请人地址: Neuhofweg 11 4102 Binningen CH
- 专利权人: Basilea Pharmaceutica AG
- 当前专利权人: Basilea Pharmaceutica AG
- 当前专利权人地址: Neuhofweg 11 4102 Binningen CH
- 代理机构: Schager, Frank, Dr.
- 优先权: EP97103436 19970303
- 国际公布: WO98039328 19980911
- 主分类号: C07D403/10
- IPC分类号: C07D403/10 ; A61K31/505 ; C07D405/14 ; C07D403/14 ; C07D401/14
摘要:
The invention is concerned with compounds of general formula (I), wherein R1 signifies lower-alkoxy, R2 signifies hydroxy or lower-alkoxy, R3 signifies hydrogen, cyano, alkyl, alkenyl, cycloalkyl, aryl, heterocycyl, aralkyl, aryl-Q-alkyl, heterocyclalkyl or a group of the formula -(CH¿2?)n-, Q signifies -SO-; R?4, R4'? each independently signify hydrogen, alkyl, aryl or heterocyclalkyl, R?5¿ signifies hydrogen, alkyl, alkoxy, aryl or heterocycyl, or R?4 and R5¿ together can form a group -(CH¿2?)n-, and n is a whole number of 2 to 5, as well as pharmaceutically usable salts thereof; the use of these compounds and their salts as therapeutically active substances; medicaments based on these substances and their production; the use of these substances as medicaments and for the production of antibacterially-active medicaments; as well as the manufacture of the compounds of formula (I) and their pharmaceutically acceptable salts and intermediates for their manufacture.
公开/授权文献
- EP0966464A1 SUBSTITUTED 2,4-DIAMINOPYRIMIDINES 公开/授权日:1999-12-29
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