发明公开
- 专利标题: 4-PHENYLPIPERIDINE COMPOUNDS
- 专利标题(中): 4-苯基衍生物
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申请号: EP97926276.3申请日: 1997-06-10
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公开(公告)号: EP0994872A1公开(公告)日: 2000-04-26
- 发明人: BENNEKER, Franciscus, Bernardus, Gemma , VAN DALEN, Frans , LEMMENS, Jacobus, Maria , PETERS, Theodorus, Hendricus, Antonium , PICHA, Frantisek
- 申请人: Synthon B.V.
- 申请人地址: Microweg 22 6545 CM Nijmegen NL
- 专利权人: Synthon B.V.
- 当前专利权人: Synthon B.V.
- 当前专利权人地址: Microweg 22 6545 CM Nijmegen NL
- 代理机构: Duxbury, Stephen
- 国际公布: WO9856787 19981217
- 主分类号: C07D405/12
- IPC分类号: C07D405/12 ; A61K31/445
摘要:
The invention relates to a compound, and pharmaceutically acceptable salts, having formula (I), wherein: R represents an alkyl or alkynyl group having 1-4 carbon atoms, or a phenyl group optionally substituted by C1-4 alkyl, alkylthio, alkoxy, halogen, nitro, acylamino, methylsulfonyl or methylenedioxy, or represents tetrahydronaphthyl; R1 represents hydrogen, trifluoro (C¿1-4?) alkyl, alkyl or alkynyl; X represents hydrogen, alkyl having 1-4 carbon atoms, alkoxy, trifluoroalkyl, hydroxy, halogen, methylthio or aralkoxy; R?2¿ represents: a C¿1?-C10 alkyl group; a phenyl group optionally substituted by one or more of the following groups: a C1-C10 alkyl group, a halogen group, a nitro group, hydroxy group, and/or an alkoxy group.
公开/授权文献
- EP0994872B9 4-PHENYLPIPERIDINE COMPOUNDS 公开/授权日:2001-12-05
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