发明公开
EP1003745A1 NAPHTHYRIDINONES FOR INHIBITING PROTEIN TYROSINE KINASE AND CELL CYCLE KINASE MEDIATED CELLULAR PROLIFERATION
有权
，用来抑制蛋白酪氨酸激酶和细胞周期激酶Naphthyridinones引起细胞增殖
- 专利标题： NAPHTHYRIDINONES FOR INHIBITING PROTEIN TYROSINE KINASE AND CELL CYCLE KINASE MEDIATED CELLULAR PROLIFERATION
- 专利标题（中）： ，用来抑制蛋白酪氨酸激酶和细胞周期激酶Naphthyridinones引起细胞增殖
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申请号： EP98939941.5申请日： 1998-08-13
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公开(公告)号： EP1003745A1公开(公告)日： 2000-05-31
- 发明人: BARVIAN, Mark, Robert , DENNY, William, Alexander , DOBRUSIN, Ellen, Myra , HAMBY, James, Marino , SHOWALTER, Howard, Daniel, Hollis , THOMPSON, Andrew, Mark , WINTERS, Roy, Thomas , WU, Zhipei
- 申请人： WARNER-LAMBERT COMPANY
- 申请人地址： 201 Tabor Road Morris PlainsNew Jersey 07950 US
- 专利权人： WARNER-LAMBERT COMPANY
- 当前专利权人： WARNER-LAMBERT COMPANY
- 当前专利权人地址： 201 Tabor Road Morris PlainsNew Jersey 07950 US
- 代理机构： Tesch, Rudolf, Dr.
- 优先权： US56746P 19970820
- 国际公布： WO9909030 19990225
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/44
摘要：
Naphthyridinones of Formula (I) are inhibitors of PTKs and cell cycle kinases, and are useful in treating cellular proliferation. The compounds are especially useful in treating cancer, atherosclerosis, restenosis, and psoriasis.
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