发明公开
EP1009742A1 5,5-DISUBSTITUTED-1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONES USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS
审中-公开
5,5-二取代1,5-二氢-4,1- BENZOXAZEPI N-2(3H) - 酮和它们作为HIV逆转录酶INHIBITORS-
- 专利标题: 5,5-DISUBSTITUTED-1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONES USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS
- 专利标题(中): 5,5-二取代1,5-二氢-4,1- BENZOXAZEPI N-2(3H) - 酮和它们作为HIV逆转录酶INHIBITORS-
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申请号: EP98942117.7申请日: 1998-08-19
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公开(公告)号: EP1009742A1公开(公告)日: 2000-06-21
- 发明人: COCUZZA, Anthony, Joseph , RODGERS, James, David
- 申请人: Du Pont Pharmaceuticals Company
- 申请人地址: 974 Centre Road, WR-1st 18 Wilmington, DE 19807 US
- 专利权人: Du Pont Pharmaceuticals Company
- 当前专利权人: Du Pont Pharmaceuticals Company
- 当前专利权人地址: 974 Centre Road, WR-1st 18 Wilmington, DE 19807 US
- 代理机构: Jones, Alan John
- 优先权: US57431P 19970902
- 国际公布: WO9911635 19990311
- 主分类号: C07D267/14
- IPC分类号: C07D267/14 ; C07D413/06 ; C07D498/04 ; A61K31/55
摘要:
The present invention relates to benzoxazepinones of formula (I), or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same and methods of using the same for treating viral infection or as an assay standard or reagent.
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