发明公开
EP1028110A1 NOVEL DIHYDRONAPHTHALENE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME
有权
德国维多利亚州德黑兰DERSELBEN
- 专利标题： NOVEL DIHYDRONAPHTHALENE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME
- 专利标题（中）： 德国维多利亚州德黑兰DERSELBEN
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申请号： EP98945556.3申请日： 1998-10-01
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公开(公告)号： EP1028110A1公开(公告)日： 2000-08-16
- 发明人: HARTMANN, Rolf, Wolfgang , WACHALL, Bertil , YOSHIHAMA, Makoto , NAKAKOSHI, Masamichi , NOMOTO, Shin, 2-303, Erumezon gakuenminami , IKEDA, Yoshikazu
- 申请人： Yukijirushi Nyugyo Kabushiki Kaisha
- 申请人地址： 1-1, Naebocho 6-chome Higashi-ku, Sapporo-shi, Hokkai-do 065-0043 JP
- 专利权人： Yukijirushi Nyugyo Kabushiki Kaisha
- 当前专利权人： Yukijirushi Nyugyo Kabushiki Kaisha
- 当前专利权人地址： 1-1, Naebocho 6-chome Higashi-ku, Sapporo-shi, Hokkai-do 065-0043 JP
- 代理机构： VOSSIUS & PARTNER
- 优先权： JP28426397 19971002
- 国际公布： WO9918075 19990415
- 主分类号： C07D213/16
- IPC分类号： C07D213/16 ; C07C13/48 ; C07C39/23 ; C07C43/21 ; C07D233/64 ; A61K31/44 ; A61K31/415 ; A61K31/025
摘要：
Dihydronaphthalene compounds have excellent 17α-hydroxylase/C 17-20 -lyase inhibiting activity, thromboxan A 2 synthesis inhibiting activity, and aromatase inhibiting activity and are thereby are useful as preventive and/or therapeutic agents for various male sex hormone- and female sex hormone-dependent diseases such as prostate cancer, prostatomegaly, masculinization, breast cancer, mastopathy, uterine cancer, endometriosis, and ovarian cancer, as well as myocardial infarction, angina pectoris, and bronchial asthma.
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