发明公开
EP1029853A1 Heteroaromatic bicyclic derivatives useful as anticancer agents
有权
Heteroaromatische bizyklische Verbindungen mit Antikrebswirkung
- 专利标题： Heteroaromatic bicyclic derivatives useful as anticancer agents
- 专利标题（中）： Heteroaromatische bizyklische Verbindungen mit Antikrebswirkung
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申请号： EP99310574.1申请日： 1999-12-24
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公开(公告)号： EP1029853A1公开(公告)日： 2000-08-23
- 发明人: Kath, John Charles , Tom, Norma Jacqueline , Cox, Eric David , Bhattacharya, Samit Kumar
- 申请人： Pfizer Products Inc.
- 申请人地址： Eastern Point Road Groton, Connecticut 06340 US
- 专利权人： Pfizer Products Inc.
- 当前专利权人： Pfizer Products Inc.
- 当前专利权人地址： Eastern Point Road Groton, Connecticut 06340 US
- 代理机构： Ruddock, Keith Stephen
- 优先权： US117341P 19990127
- 主分类号： C07D239/94
- IPC分类号： C07D239/94 ; C07D453/02 ; C07D451/02 ; A61K31/505 ; A61P35/00
摘要：
The invention relates to compounds of the formula 1
and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R 1 , R 3 and R 4 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1 . The invention also relates to methods of preparing the compounds of formula 1 .
and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R 1 , R 3 and R 4 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1 . The invention also relates to methods of preparing the compounds of formula 1 .
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