发明授权
- 专利标题： TREATMENT OF NEOPLASMS WITH INTERFERON-SENSITIVE, CLONAL VIRUSES
- 专利标题（中）： 肿瘤干扰素敏感的克隆病毒治疗
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申请号： EP98949797.9申请日： 1998-10-09
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公开(公告)号： EP1032269B1公开(公告)日： 2007-08-29
- 发明人: ROBERTS, Michael, S. , LORENCE, Robert, M. , GROENE, William, S. , RABIN, Harvey , VON BORSTEL, Reid, W.
- 申请人： Wellstat Biologics Corporation
- 申请人地址： 930 Clopper Road Gaithersburg, MD 20878 US
- 专利权人： Wellstat Biologics Corporation
- 当前专利权人： Wellstat Biologics Corporation
- 当前专利权人地址： 930 Clopper Road Gaithersburg, MD 20878 US
- 代理机构： MacLean, Martin Robert
- 优先权： US948244 19971009
- 国际公布： WO1999018799 19990422
- 主分类号： A01N63/00
- IPC分类号： A01N63/00 ; A61K35/76 ; C12N7/00 ; C12N7/02
摘要：
The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumours. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
公开/授权文献
- EP1032269A1 TREATMENT OF NEOPLASMS WITH VIRUSES 公开/授权日：2000-09-06
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