发明公开
- 专利标题： CARBOHYDRATE DERIVATIVES
- 专利标题（中）： KOOLHYDRAT衍生物
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申请号： EP98958248.1申请日： 1998-11-16
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公开(公告)号： EP1032579A1公开(公告)日： 2000-09-06
- 发明人: VAN BOECKEL, Constant, Adriaan, Anton , PETITOU, Maurice , DUCHAUSSOY, Philippe , DREEF-TROMP, Cornelia, Maria , BASTEN, Johannes, Egbertus, Maria
- 申请人： Akzo Nobel N.V. , Sanofi-Synthélabo
- 申请人地址： Velperweg 76 6824 BM Arnhem NL
- 专利权人： Akzo Nobel N.V.,Sanofi-Synthélabo
- 当前专利权人： Akzo Nobel N.V.,Sanofi-Synthélabo
- 当前专利权人地址： Velperweg 76 6824 BM Arnhem NL
- 代理机构： Hogenbirk, Marijke
- 优先权： EP97203613 19971119
- 国际公布： WO9925720 19990527
- 主分类号： C07H3/06
- IPC分类号： C07H3/06 ; A61K31/70 ; C07H11/00 ; C07H15/04
摘要：
The invention relates to a carbohydrate derivative having formula (I) wherein R1 is (1-4C)alkoxy; R?2, R3 and R4¿ are independently (1-4C)alkoxy or OSO¿3?-; the total number of sulfate groups is 4, 5 or 6; and the twisted lines represent bonds either above or below the plane of the six-membered ring to which they are attached; or a pharmaceutically acceptable salt thereof. The compounds of the invention have antithrombotic activity and may be used for treating or preventing thrombosis and for inhibiting smooth muscle cell proliferation.
公开/授权文献
- EP1032579B1 CARBOHYDRATE DERIVATIVES 公开/授权日：2003-05-02
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