发明公开
- 专利标题: NITROGEN-CONTAINING TETRACYCLIC COMPOUNDS
- 专利标题(中): 含氮四环CONNECTIONS
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申请号: EP98957146申请日: 1998-12-03
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公开(公告)号: EP1048651A4公开(公告)日: 2001-09-19
- 发明人: NAKAZATO ATSURO , OKUBO TAKETOSHI , KUMAGAI TOSHIHITO , CHAKI SHIGEYUKI , TOMISAWA KAZUYUKI , NAGAMINE MASASHI , GOTOH MAKOTO , KONDOH KUNIAKI , YOSHIDA MASANORI
- 申请人: TAISHO PHARMA CO LTD , NIHON NOHYAKU CO LTD
- 专利权人: TAISHO PHARMA CO LTD,NIHON NOHYAKU CO LTD
- 当前专利权人: TAISHO PHARMA CO LTD,NIHON NOHYAKU CO LTD
- 优先权: JP33253897 1997-12-03
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; C07D491/052 ; C07D495/04 ; C07D209/80 ; A61K31/40 ; A61K31/415 ; A61K31/435 ; A61K31/495 ; C07D209/82 ; C07D487/04 ; C07D513/04
摘要:
Nitrogen-containing tetracyclic compounds represented by general formula (I) or pharmaceutically acceptable salts thereof, wherein Y1-Y2-Y3 represents N-C=N or C=C-NR3 (wherein R3 represents hydrogen, C¿1-5? alkyl or nitrogen-containing C2-10 alkyl); Y?4¿ represents S, SO, SO¿2?, CH2 or NR?4¿ (wherein R4 represents C¿1-5? alkanoyl or C1-5 alkyl); R?1 and R2¿ are the same or different and each represents hydrogen, C¿1-10? alkyl, C3-15 alkoxyalkyl or C3-15 alkylaminoalkyl, or R?1 and R2¿ form together with the adjacent nitrogen atom cyclic amino; X?1 and X2¿ are the same or different and each represents hydrogen, C¿1-5? alkyl, C1-5 alkoxy or halogeno; and n is 0, 1 or 2.
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