发明公开
EP1052250A1 Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
失效
磺酰基烷酰基氨基 - 羟乙基氨基 - 磺酰胺als Inhibitoren der retroviralen Protease
- 专利标题： Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
- 专利标题（中）： 磺酰基烷酰基氨基 - 羟乙基氨基 - 磺酰胺als Inhibitoren der retroviralen Protease
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申请号： EP00114155.5申请日： 1996-03-07
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公开(公告)号： EP1052250A1公开(公告)日： 2000-11-15
- 发明人: Getman, Daniel P. , Decrescenzo, Gary A. , Freskos, John N. , Vazquez, Michael L. , Sikorski, James A. , Devadas, Balkudru , Nagarajan, Srinivasan , McDonald, Joseph J.
- 申请人： G.D. SEARLE & CO.
- 申请人地址： P.O. Box 5110 Chicago, IL 60680-5110 US
- 专利权人： G.D. SEARLE & CO.
- 当前专利权人： G.D. SEARLE & CO.
- 当前专利权人地址： P.O. Box 5110 Chicago, IL 60680-5110 US
- 代理机构： Beil, Hans Christoph, Dr.
- 优先权： US401838 19950310; US478625 19950607
- 主分类号： C07C311/00
- IPC分类号： C07C311/00 ; C07D317/62 ; C07D319/18 ; C07D277/64 ; C07D307/82 ; C07D235/32 ; C07D277/82 ; A61K31/34 ; A61K31/36 ; A61K31/415 ; A61K31/425
摘要：
Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.
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