发明公开
EP1054877A1 NOVEL CYCLIC SULFONAMIDE DERIVATIVES AS METALLOPROTEINASE INHIBITORS
审中-公开
循环磺酰胺衍生物金属蛋白酶抑制剂
- 专利标题： NOVEL CYCLIC SULFONAMIDE DERIVATIVES AS METALLOPROTEINASE INHIBITORS
- 专利标题（中）： 循环磺酰胺衍生物金属蛋白酶抑制剂
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申请号： EP99905898.5申请日： 1999-02-10
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公开(公告)号： EP1054877A1公开(公告)日： 2000-11-29
- 发明人: DUAN, Jingwu , CHEN, Lihua , CHERNEY, Robert, J. , DECICCO, Carl, P. , VOSS, Matthew, E.
- 申请人： Du Pont Pharmaceuticals Company
- 申请人地址： 974 Centre Road, WR-1st 18 Wilmington, DE 19807 US
- 专利权人： Du Pont Pharmaceuticals Company
- 当前专利权人： Du Pont Pharmaceuticals Company
- 当前专利权人地址： 974 Centre Road, WR-1st 18 Wilmington, DE 19807 US
- 代理机构： Beacham, Annabel Rose
- 优先权： US74301P 19980211
- 国际公布： WO9941246 19990819
- 主分类号： C07D285/36
- IPC分类号： C07D285/36 ; C07D279/02 ; C07D417/12 ; C07D417/06 ; A61K31/55 ; A61K31/54
摘要：
The present application describes novel lactams and derivatives thereof of formula (I) or pharmaceutically acceptable salt forms thereof, wherein ring B is a 4-8 membered cyclic sulfonamide containing from 0-3 additional heteroatoms selected from N, O, and S, which are useful as metalloprotease inhibitors.
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