发明公开
EP1061806A1 PRODUCER CELLS FOR REPLICATION SELECTIVE VIRUSES IN THE TREATMENT OF MALIGNANCY
审中-公开
FOR REPLICATION选择性病毒生产性细胞用于治疗恶性病变
- 专利标题： PRODUCER CELLS FOR REPLICATION SELECTIVE VIRUSES IN THE TREATMENT OF MALIGNANCY
- 专利标题（中）： FOR REPLICATION选择性病毒生产性细胞用于治疗恶性病变
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申请号： EP99911363.2申请日： 1999-03-12
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公开(公告)号： EP1061806A1公开(公告)日： 2000-12-27
- 发明人: MOLNAR-KIMBER, Katherine, L. , CAPARRELLI, David J. , KAISER, Larry, R. , ALBELDA, Steven, M. , COUKOS, George
- 申请人： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- 申请人地址： University of Pennsylvania,Suite 300,3700 Market Street Philadelphia,Pennsylvania 19104-3147 US
- 专利权人： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- 当前专利权人： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- 当前专利权人地址： University of Pennsylvania,Suite 300,3700 Market Street Philadelphia,Pennsylvania 19104-3147 US
- 代理机构： Grünecker, Kinkeldey, Stockmair & SchwanhäusserAnwaltssozietät
- 优先权： US77681P 19980312
- 国际公布： WO9945783 19990916
- 主分类号： A01N63/00
- IPC分类号： A01N63/00 ; C12N1/20 ; C12N15/00 ; C12P21/06
摘要：
The invention includes producer cells for administering to a subject having tumor cells in order to kill tumor cells or prevent growth or spread of the tumor. The producer cell comprises an oncolytic virus which is capable of replicating in the producer cell. The producer cell is not capable of sustained survival in the body of the subject. The invention also includes methods of using these producer cells to treat a subject having tumor cells and making a medicament for use in such treatment.
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