发明公开
EP1075514A1 MODIFYING THE EXPRESSION OF THE FSH BETA GENE BY HOMOLOGOUS RECOMBINATION
审中-公开
通过同源重组表达BETA FSH基因的改性
- 专利标题： MODIFYING THE EXPRESSION OF THE FSH BETA GENE BY HOMOLOGOUS RECOMBINATION
- 专利标题（中）： 通过同源重组表达BETA FSH基因的改性
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申请号： EP99921670.8申请日： 1999-05-05
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公开(公告)号： EP1075514A1公开(公告)日： 2001-02-14
- 发明人: TRECO, Douglas, A. , HEARTLEIN, Michael, W. , SELDEN, Richard, F.
- 申请人： TRANSKARYOTIC THERAPIES, INC.
- 申请人地址： 195 Albany Street Cambridge, MA 02139 US
- 专利权人： TRANSKARYOTIC THERAPIES, INC.
- 当前专利权人： TRANSKARYOTIC THERAPIES, INC.
- 当前专利权人地址： 195 Albany Street Cambridge, MA 02139 US
- 代理机构： Grund, Martin, Dr.
- 优先权： US84663P 19980507
- 国际公布： WO9957263 19991111
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; C12N5/10 ; C12N15/67 ; C12N15/85 ; C07K14/59 ; A61K48/00
摘要：
An isolated nucleic acid molecule that hybridizes under stringent conditions, or shares at least 80 % sequence identity, with a defined genomic region upstream of the coding region of a FSHβ gene, and a DNA construct containing that nucleic acid molecule as a targeting sequence for homologous recombination.
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