- 专利标题: NEUROTROPHIC GROWTH FACTOR
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申请号: EP99938261.7申请日: 1999-07-14
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公开(公告)号: EP1097167B2公开(公告)日: 2018-12-12
- 发明人: GEERTS, Hugo Alfonso , MASURE, Stefan, Leo, Jozef , MEERT, Theo Frans , CIK, Miroslav , VER DONCK, Luc, August, Laurentius
- 申请人: Janssen Pharmaceutica NV
- 申请人地址: Turnhoutseweg 30 2340 Beerse BE
- 专利权人: Janssen Pharmaceutica NV
- 当前专利权人: Janssen Pharmaceutica NV
- 当前专利权人地址: Turnhoutseweg 30 2340 Beerse BE
- 代理机构: Boult Wade Tennant LLP
- 优先权: GB9815283 19980714; US248772 19990212; US327668 19990608
- 国际公布: WO2000004050 20000127
- 主分类号: C07K14/475
- IPC分类号: C07K14/475 ; C12N15/11 ; C12N15/63 ; C12N5/16 ; A61K38/18 ; G01N33/53 ; G01N33/68 ; C12Q1/68
摘要:
There is disclosed an isolated nucleic acid molecule encoding a human neurotrophic growth factor designated enovin and having the amino acid sequence illustrated in Figure 1, 21, 23 or 24 or encoding a functional equivalent, derivative or bioprecursor of said growth factor. The growth factor preferably comprises the amino acid sequence from position 27 to 139 of the sequence illustrated in Figure 1, or a functional equivalent, derivative or bioprecursor thereof. The nucleic acid molecule encoding enovin can be used to transform a host cell, tissue or organism by including it in an appropriate vector. The host cell, tissue or organism and the vector also form part of the invention.
公开/授权文献
- EP1097167B1 NEUROTROPHIC GROWTH FACTOR 公开/授权日:2006-10-25
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