发明公开
- 专利标题: Oil-based adjuvant vaccine
- 专利标题(中): Öladjuvierter疫苗
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申请号: EP00123909.4申请日: 2000-11-03
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公开(公告)号: EP1097721A3公开(公告)日: 2001-05-23
- 发明人: Saito, Koichi , Kishimoto, Yoko , Miyahara, Tokuji , Takase, Kouzou
- 申请人: NOF CORPORATION , Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute
- 申请人地址: 20-3, Ebisu 4-chome, Shibuya-ku Tokyo 150-6019 JP
- 专利权人: NOF CORPORATION,Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人: NOF CORPORATION,Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人地址: 20-3, Ebisu 4-chome, Shibuya-ku Tokyo 150-6019 JP
- 代理机构: von Kreisler, Alek, Dipl.-Chem.
- 优先权: JP31612199 19991105
- 主分类号: A61K9/113
- IPC分类号: A61K9/113
摘要:
The present invention provides a W/O/W type oil adjuvant vaccine containing an outer aqueous phase containing 0.5 wt% - 20 wt% of a polyethylene glycol derivative having a molecular weight of 400 - 20,000, and an inner aqueous phase containing a biologically acceptable and effective amount of an antigen. The constitution of the present invention that a polyethylene glycol derivative having a specific molecular weight is contained in the outer aqueous phase enables preparation of a W/O/W type oil adjuvant vaccine showing a high adjuvant effect, reduced side effects such as topical response, superior preparation stability and superior workability to allow a person to give an injection easily due to the lowered viscosity.
公开/授权文献
- EP1097721B1 Oil-based adjuvant vaccine 公开/授权日:2003-05-14
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