发明公开
- 专利标题： CYANOIMINOQUINOXALINE DERIVATIVES
- 专利标题（中）： 氰基亚氨基喹啉衍生物
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申请号： EP99922540.2申请日： 1999-05-28
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公开(公告)号： EP1097927A1公开(公告)日： 2001-05-09
- 发明人: TAKADA, Susumu , CHOMEI, Nobuo , KIHARA, Tsuyoshi
- 申请人： SHIONOGI & CO., LTD.
- 申请人地址： 1-8, Doshomachi 3-chome, Chuo-ku Osaka-shi, Osaka 541-0045 JP
- 专利权人： SHIONOGI & CO., LTD.
- 当前专利权人： SHIONOGI & CO., LTD.
- 当前专利权人地址： 1-8, Doshomachi 3-chome, Chuo-ku Osaka-shi, Osaka 541-0045 JP
- 代理机构： VOSSIUS & PARTNER
- 优先权： JP15101798 19980601
- 国际公布： WO9962887 19991209
- 主分类号： C07D241/44
- IPC分类号： C07D241/44 ; A61K31/495
摘要：
A cyanoiminoquinoxaline derivative of the formula (II) is useful as a preventive or therapeutic agent for diseases due to hyperexcitation of glutamate receptors.
(wherein, X and Y each is independently O or NCN, provided that at least one of X and Y is NCN; R 1 , R 2 , R 3 , and R 4 each is independently hydrogen, halogen, nitro, optionally substituted heterocyclic group etc.; R 5 is hydrogen etc.; R 1 and R 2 , R 2 and R 3 , R 3 and R 4 , and R 4 and R 5 , each taken together with the adjacent atoms may form a carbocycle which may be substituted or may contain a heteroatom(s).)
(wherein, X and Y each is independently O or NCN, provided that at least one of X and Y is NCN; R 1 , R 2 , R 3 , and R 4 each is independently hydrogen, halogen, nitro, optionally substituted heterocyclic group etc.; R 5 is hydrogen etc.; R 1 and R 2 , R 2 and R 3 , R 3 and R 4 , and R 4 and R 5 , each taken together with the adjacent atoms may form a carbocycle which may be substituted or may contain a heteroatom(s).)
公开/授权文献
- EP1097927B1 CYANOIMINOQUINOXALINE DERIVATIVES 公开/授权日：2006-07-19
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