To combat weeds in soybean crops consisting of tolerant or resistant mutants or transgenic soybean plants, herbicide combinations (A)+(B) can be used, possibly in the presence of safeners, which contain an active quantity of (A) broad-spectrum herbicides from the group of (A1) glufosinates, their salts and related compounds, (A2) glyphosates, their salts and related compounds such as sulfosates, (A3) imidazolinones such as imazethapyr, imazapyr, imazaquine, imazamox or their salts and (A4) herbicidal azoles from the group of the protoporphyrinogen-oxidase inhibitors (PPO inhibitors); and (B) one or more herbicides from the group of (B0) one or more structurally different herbicides from the above group (A) and/or (B1) leaf-effective and/or soil-effective (residually active) herbicides which are selectively active in soybean against monocotyledonous and primarily dicotyledonous weeds, or (B2) herbicides selectively active in soybean against dicotyledonous weeds or (B3) leaf- and/or soil-effective herbicides selectively active in soybean against monocotyledonous weeds or (B4) leaf-effective herbicides selectively active in soybean against monocotyledonous and dicotyledonous weeds, or (B5) non-selective herbicides, such as paraquat (salts), which can be used for specific purposes in soybean, or herbicides from several of the groups (B0) to (B5). Said soybean crops are tolerant to the herbicides (A) and (B) contained in the combination, possibly in the presence of safeners.