发明公开
- 专利标题: PEPTIDE FRAGMENTS HAVING CELL DEATH INHIBITORY ACTIVITY
- 专利标题(中): 与细胞死亡抑制活性肽片段
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申请号: EP99972642申请日: 1999-11-12
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公开(公告)号: EP1132402A4公开(公告)日: 2005-12-21
- 发明人: HIRASHIMA MASAKI , MAEDA HIROAKI , NOZAKI CHIKATERU
- 申请人: CHEMO SERO THERAPEUT RES INST
- 专利权人: CHEMO SERO THERAPEUT RES INST
- 当前专利权人: CHEMO SERO THERAPEUT RES INST
- 优先权: JP34786398 1998-11-19
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/47 ; A61K38/17 ; C07K16/18 ; C12N5/06
摘要:
Peptide fragment(s) having an activity of inhibiting cell death which contain the amino acid sequence consisting of 103 amino acid residues in the C-terminal side of selenoprotein P, an amino acid sequence derived from the above amino acid sequence by deletion, substitution or addition of one or several amino acids therein, or a partial sequence of either of the above amino acid sequences; remedies containing the above peptide fragment(s); antibodies against the above peptide fragment(s); and a method for screening a cell death inhibitory activity with the use of the above peptide fragment(s). Preferable examples of the above peptide fragment(s) are those containing the amino acid sequence(s) represented by SEQ ID NO:1 and/or 2 or partial sequences thereof.
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