发明授权
- 专利标题： VERFAHREN ZUM HERSTELLEN FESTER DARREICHUNGSFORMEN MITTELS SCHMELZEXTRUSION
- 专利标题（英）： Method for producing solid forms of administration by melt extrusion
- 专利标题（中）： 法生产固体剂型通过熔体挤出
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申请号： EP99966909.6申请日： 1999-11-30
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公开(公告)号： EP1135109B1公开(公告)日： 2003-04-02
- 发明人: BERNDL, Gunther , KOTHRADE, Stephan , KESSLER, Thomas , LANGE, Armin , HOFMANN, Jürgen , REINHOLD, Ulrich
- 申请人： BASF AKTIENGESELLSCHAFT
- 申请人地址： 67056 Ludwigshafen DE
- 专利权人： BASF AKTIENGESELLSCHAFT
- 当前专利权人： BASF AKTIENGESELLSCHAFT
- 当前专利权人地址： 67056 Ludwigshafen DE
- 代理机构： Kinzebach, Werner, Dr.
- 优先权： DE19855440 19981201
- 国际公布： WO00032169 20000608
- 主分类号： A61K9/16
- IPC分类号： A61K9/16
摘要：
The invention relates to a method for producing solid forms of administration by means of melt extrusion. A polymer binder, at least one pharmaceutical active agent and optionally, other additives are mixed and the mixture is melted in an extruder and then extruded in the form of a continuous plastic product strand. The inventive method is characterised in that the extruder used is a planetary roller extruder (10) which preferably has one central spindle (13) and six planetary spindles (14).
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