发明授权
EP1140968B9 DNA MOLECULES ENCODING SPLICE VARIANTS OF THE HUMAN MELANOCORTIN 1 RECEPTOR PROTEIN
有权
黑皮质素1受体蛋白的DNA分子编码人剪接变体
- 专利标题： DNA MOLECULES ENCODING SPLICE VARIANTS OF THE HUMAN MELANOCORTIN 1 RECEPTOR PROTEIN
- 专利标题（中）： 黑皮质素1受体蛋白的DNA分子编码人剪接变体
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申请号： EP99963099.9申请日： 1999-12-16
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公开(公告)号： EP1140968B9公开(公告)日： 2007-05-09
- 发明人: HOWARD, Andrew, D. , MACNEIL, Douglas, J. , VAN DER PLOEG, Leonardus, H., T.
- 申请人： Merck & Co., Inc.
- 申请人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 代理机构： Horgan, James Michael Frederic
- 优先权： US113401P 19981223
- 国际公布： WO2000039147 20000706
- 主分类号： C07K14/72
- IPC分类号： C07K14/72
摘要：
The present invention relates to DNA molecules encoding splice variants of the melanocortin-1 receptor (MC-R1) protein belonging to the rhodopsin sub-family of G-protein coupled receptors, recombinant vectors comprising DNA molecules encoding MC-R1B protein, recombinant host cells which contain a recombinant vector encoding MC-R1B, the human MC-R1B protein encoded by the DNA molecule, and methods of identifying selective agonists and antagonists of MC-R1B proteins disclosed throughout this specification.
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