发明公开
EP1142875A4 CINNAMAMIDE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME
审中-公开
IN ID TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN
- 专利标题： CINNAMAMIDE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME
- 专利标题（中）： IN ID TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN TEN
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申请号： EP00900175申请日： 2000-01-11
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公开(公告)号： EP1142875A4公开(公告)日： 2003-03-26
- 发明人: HASEGAWA YOSHIHIRO , SHINDOU SHOUICHIROU , HATTORI TOMOHISA , OBATA TATSUHIRO , HORIUCHI FUMIKO , HAYAKAWA HIROYUKI , KUMAZAWA HIROAKI
- 申请人： TSUMURA & CO
- 专利权人： TSUMURA & CO
- 当前专利权人： TSUMURA & CO
- 优先权： JP438499 1999-01-11
- 主分类号： A61P9/00
- IPC分类号： A61P9/00 ; A61P11/00 ; A61P13/12 ; A61P37/02 ; C07D213/40 ; A61K31/44 ; A61K31/4406
摘要：
Cinnamamide derivatives represented by general formula (I); and immunomodulators and preventive and therapeutic agents for nephrotic syndrome, circulatory disturbance and respiratory diseases, containing the same, wherein R1 is hydroxyl, C¿1?-C6 alkoxy, arylalkoxy or (substituted) amino; R?2 and R3¿ are each halogeno or C¿1?-C4 alkyl; R?4¿ is hydrogen or C¿1?-C6 alkyl; R?5¿ is hydrogen, C¿1?-C6 alkyl or aryl; R?6¿ is hydrogen, C¿1?-C6 alkyl, cyano or C1-C6 alkoxycarbonyl; W is O, S, imino, methylene, hydroxymethylene or carbonyl; X and Y are each O or S; m is an integer of 0 to 2; and n is an integer of 1 to 3, or alternatively the -C(R?2)(R3¿)-W- group may be vinylene when m is 0.
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