发明公开
- 专利标题: NEUTROKINE-ALPHA AND NEUTROKINE-ALPHA SPLICE VARIANT
- 专利标题(中): Neutrokin-α和Neutrokin-α剪接变体
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申请号: EP00908739申请日: 2000-02-22
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公开(公告)号: EP1157110A4公开(公告)日: 2006-05-10
- 发明人: ROSEN CRAIG A , NI JIAN , EBNER REINHARD , YU GUO-LIANG
- 申请人: HUMAN GENOME SCIENCES INC
- 专利权人: HUMAN GENOME SCIENCES INC
- 当前专利权人: HUMAN GENOME SCIENCES INC
- 优先权: US25579499 1999-02-23; US12238899 1999-03-02; US12409799 1999-03-12; US12659999 1999-03-26; US12759899 1999-04-02; US13041299 1999-04-16; US13069699 1999-04-23; US13127899 1999-04-27; US13167399 1999-04-29; US13678499 1999-05-28; US14265999 1999-07-06; US14582499 1999-07-27; US16723999 1999-11-24; US16862499 1999-12-03; US17110899 1999-12-16; US17162699 1999-12-23; US17601500 2000-01-14
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K38/00 ; A61K38/19 ; A61P31/00 ; A61P35/04 ; A61P37/02 ; A61P37/04 ; A61P37/06 ; C07K14/52 ; C07K14/715 ; C07K16/24 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12N15/19 ; C12P21/02
摘要:
The present invention relates to a novel cytokine which has been designated Neutrokine-alpha ("Neutrokine-alpha"). In addition, an apparent splicing variant of Neutrokine-alpha has been identified and designated Neutrokine-alphaSV. In specific embodiments, the present invention provides nucleic acid molecules encoding Neutrokine-alpha and Neutrokine-alphaSV polypeptides. In additional embodiments, Neutrokine-alpha and Neutrokine-alphaSV polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same.
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