发明授权
EP1161434B1 DERIVES DE PYRIDOPYRANOAZEPINES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
有权
PYRIDOPYRANOAZEPINDERIVATE，生产和治疗用途
- 专利标题： DERIVES DE PYRIDOPYRANOAZEPINES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
- 专利标题（英）： Pyridopyranoazepine derivatives, preparation and therapeutic use
- 专利标题（中）： PYRIDOPYRANOAZEPINDERIVATE，生产和治疗用途
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申请号： EP00907746.2申请日： 2000-03-01
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公开(公告)号： EP1161434B1公开(公告)日： 2003-01-29
- 发明人: GALLI, Frédéric , JEGHAM, Samir , LOCHEAD, Alistair , SAMSON, Axelle
- 申请人： SANOFI-SYNTHELABO
- 申请人地址： 174, Avenue de France 75013 Paris FR
- 专利权人： SANOFI-SYNTHELABO
- 当前专利权人： SANOFI-SYNTHELABO
- 当前专利权人地址： 174, Avenue de France 75013 Paris FR
- 代理机构： Ludwig, Jacques
- 优先权： FR9902784 19990305
- 国际公布： WO00053608 20000914
- 主分类号： C07D491/22
- IPC分类号： C07D491/22 ; A61K31/44 ; A61P25/00
摘要：
The invention concerns compounds of general formula (I) wherein: R1 represents a hydrogen atom, an alkyl, phenylalkyl, phenylhydroxyalkyl, furanylalkyl or furanylhydroxyalkyl group; R2 represents either a hydrogen or a halogen atom or a trifluoromethyl, cyano, hydroxy, nitro, acetyl, alkoxy, amino group of general formula NR4R5 wherein: R4 and R5 represent each a hydrogen atom or an alkyl group or form, with the nitrogen atom which bears them, a C4-C7 cycle, or a phenyl or naphthyl group optionally substituted by a halogen atom or a trifluoromethyl, trifluoromethoxy, cyano, hydroxy, nitro, acetyl alkyl, alkoxy, or methylenedioxy group; and R3 represents a hydrogen or halogen atom or an alkyl group.
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