发明公开
EP1163522A1 DETECTION D'UNE ACTIVITE SUPERANTIGENIQUE DANS UN ECHANTILLON BIOLOGIQUE
有权
一个MSRV1超抗原诱导活性在生物样品检测
- 专利标题: DETECTION D'UNE ACTIVITE SUPERANTIGENIQUE DANS UN ECHANTILLON BIOLOGIQUE
- 专利标题(英): Method for detecting superantigen activity in a biological sample
- 专利标题(中): 一个MSRV1超抗原诱导活性在生物样品检测
-
申请号: EP00912720.0申请日: 2000-03-20
-
公开(公告)号: EP1163522A1公开(公告)日: 2001-12-19
- 发明人: PERRON, Hervé , LAFONT, Monique
- 申请人: BIO MERIEUX
- 申请人地址: Chemin de l'Orme 69280 Marcy l'Etoile FR
- 专利权人: BIO MERIEUX
- 当前专利权人: BIO MERIEUX
- 当前专利权人地址: Chemin de l'Orme 69280 Marcy l'Etoile FR
- 代理机构: Guerre, Dominique
- 优先权: FR9903622 19990319; FR9913755 19991028
- 国际公布: WO0057185 20000928
- 主分类号: G01N33/569
- IPC分类号: G01N33/569 ; G01N33/68 ; G01N33/50 ; G01N33/564 ; G01N33/566 ; G01N33/574 ; A61K39/00
摘要:
The invention concerns in particular a method for detecting superantigen activity in a biological sample, which consists in: demonstrating a majority spread rate of lymphocytes bearing a Vβ 16 and/or Vβ17 determinant or a majority loss rate of lymphocytes bearing a Vβ16 determinant and a method for detecting a pathological condition in a biological sample which consists in demonstrating at least one of the following parameters: a superantigen activity; a stimulation of the production of cytokines such as IL-6 and INF-η; induced cell apoptosis.
公开/授权文献
信息查询
IPC分类: