发明公开
- 专利标题： NOVEL METHOD FOR IDENTIFYING ANTIBACTERIAL COMPOUNDS
- 专利标题（中）： 一种用于识别抗菌化合物
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申请号： EP00920677.2申请日： 2000-04-07
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公开(公告)号： EP1165832A2公开(公告)日： 2002-01-02
- 发明人: LOFERER, Hannes , JACOBI, Alexander
- 申请人： GPC Biotech AG
- 申请人地址： Fraunhoferstrasse 20 82152 Martinsried DE
- 专利权人： GPC Biotech AG
- 当前专利权人： GPC Biotech AG
- 当前专利权人地址： Fraunhoferstrasse 20 82152 Martinsried DE
- 代理机构： VOSSIUS & PARTNER
- 优先权： EP99107031 19990409; EP00102111 20000204
- 国际公布： WO0061793 20001019
- 主分类号： C12Q1/18
- IPC分类号： C12Q1/18 ; C07K14/245 ; C12Q1/68
摘要：
The present invention relates to a method for identifying an antagonist or inhibitor of the expression of a gene encoding a polypeptide essential for bacterial growth or survival as well as for an antagonist or inhibitor of said polypeptide. The invention further relates to a method for improved antagonists or inhibitors. The invention also provides an antagonist or inhibitor of the activity of said polypeptide. The invention is further related to a method for producing a therapeutic agent in a composition comprising said antagonist or inhibitor. Furthermore, the invention is related to the use of the polypeptide and the antagonist or inhibitor as well as to a method to identify a surrogate marker.
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