发明公开
EP1167380A3 11.alpha.-hydroxy-steroid-4,6-dien-3-one compounds and a process for their preparation 失效
11.alpha.羟基类固醇孕甾-4,6-二烯-3-酮化合物和它们的制备方法

11.alpha.-hydroxy-steroid-4,6-dien-3-one compounds and a process for their preparation
摘要:
Compounds of Formula VIII wherein -A-A- represents the group -CHR4-CHR5- or -CR4=CR5-, R3, R4 and R5 are independently selected from the group consisting of hydrogen, halo, hydroxy, lower alkyl, lower alkoxy, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, cyano, aryloxy, -B-B- represents the group -CHR6-CHR7- or an alpha- or beta- oriented group: where R6 and R7 are independently selected from the group consisting of hydrogen, halo, lower alkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano, aryloxy, and R8 and R9 are independently selected from the group consisting of hydrogen, halo, lower alkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano, aryloxy, or R8 and R9 together comprise a carbocyclic or heterocyclic ring structure, or R8 and R9 together with R6 or R7 comprise a carbocyclic or heterocyclic ring structure fused to the pentacyclic D ring, their intermediates and processes for preparing them.
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