发明公开
EP1178971A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL URACILS AS ANTICOAGULATIVE AGENTS
审中-公开
取代POLYZYCLISCHE芳基和杂芳基尿嘧啶ALS抗凝血
- 专利标题： SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL URACILS AS ANTICOAGULATIVE AGENTS
- 专利标题（中）： 取代POLYZYCLISCHE芳基和杂芳基尿嘧啶ALS抗凝血
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申请号： EP00931917.9申请日： 2000-05-18
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公开(公告)号： EP1178971A1公开(公告)日： 2002-02-13
- 发明人: SOUTH, Michael, S. , JONES, Darin, E. , RUEPPEL, Melvin, L.
- 申请人： Pharmacia Corporation
- 申请人地址： Corporate Patent Department, P.O. Box 5110 Chicago, IL 60680 US
- 专利权人： Pharmacia Corporation
- 当前专利权人： Pharmacia Corporation
- 当前专利权人地址： Corporate Patent Department, P.O. Box 5110 Chicago, IL 60680 US
- 代理机构： Albrecht, Thomas, Dr.
- 优先权： US134957P 19990519
- 国际公布： WO0069833 20001123
- 主分类号： C07D239/54
- IPC分类号： C07D239/54 ; C07D253/06 ; C07D417/12 ; A61K31/505 ; A61P7/02
摘要：
The invention relates to substituted polycyclic aryl and heteroaryl uracil compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
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